Truth Fertility

Understanding Vaginal Microbiome and its Role in Fertility

We partner with Daye, a leading provider of female diagnostic testing, to offer vaginal microbiome testing — a simple, discreet way to better understand how your vaginal environment may be impacting fertility, implantation, and pregnancy outcomes.

Using Day’s innovative diagnostic tampon, the sample can be taken easily at home and posted directly to the laboratory. Results provide a detailed picture of the vaginal ecosystem, identifying the balance of healthy and disruptive bacteria that can affect conception and early pregnancy.

Day offer two test options:

• The Vaginal Microbiome Test, which analyses key bacterial species known to influence pregnancy outcomes.
• The Extended Vaginal Microbiome + STI Screen, which includes screening for common sexually transmitted infections alongside the full microbiome profile.

Understanding your vaginal microbiome can reveal hidden causes of recurrent implantation failure, miscarriage, or unexplained infertility — allowing for targeted treatment and improved reproductive health.

At Truth Fertility, we integrate these results with our wider diagnostic insights to provide personalised, evidence-based recommendations to optimise your fertility journey.

Why Bacterial Vaginosis Matters In Fertility

Bacterial vaginosis (BV) and BV-associated bacteria can have a profound effect on fertility and pregnancy outcomes, even in women with no obvious symptoms. Studies have shown that BV is linked to a two- to threefold increase in the risk of miscarriage and preterm birth.

A 2019 meta-analysis published in Frontiers in Cellular and Infection Microbiology found that women with BV had significantly higher odds of early pregnancy loss and adverse reproductive outcomes. Similarly, research in Human Reproduction (Klebanoff et al., 2010) and BJOG (Ralph et al., 2015) demonstrated that BV-associated organisms, such as Gardnerella vaginalis and Atopobium vaginae, are more prevalent in women experiencing recurrent miscarriage and implantation failure.

Importantly, many of our patients who test positive for BV or BV-associated bacteria are completely asymptomatic, meaning they would not otherwise have known that these imbalances were present.

By identifying and addressing these hidden microbial patterns through vaginal microbiome testing, we can take proactive steps to improve the uterine environment, reduce miscarriage risk, and support a healthier, more stable foundation for conception and pregnancy.

Fast and Affordable Treatment Access

Through our partnership with Daye, we’re able to offer patients rapid access to prescription antibiotics when bacterial imbalances are detected. Their specialist sexual health nurses review results quickly and, where appropriate, can issue same-day prescriptions — typically for a flat fee of around £45.

This ensures treatment is both accessible and affordable, allowing patients to act promptly on their results. Addressing these bacterial infections can make a meaningful difference to fertility outcomes by restoring balance within the reproductive environment for both partners.