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Trusted Sperm DNA Fragmentation Testing by Examen

We have used Examen’s Sperm DNA Fragmentation (SDF) tests since 2019 because they are the most accurate SDF tests commercially available and are used by over 80% of the top fertility clinics in the UK & Ireland.

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Sample Drop-Off Clinic Locations

We provide a DNA fragmentation testing service at the following locations.

Bristol Central Clinic

Bristol Osteopaths

BS1 4HQ

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Bristol Test Day

Monday 23rd March

Drop-off window: 12:30-13:00

Frome Clinic

Frome Therapy Rooms

BA11 1BH

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Frome Test Day

Friday 20th March

Drop-off window: 18:30-19:00

Ready to book?

Our next DNA Fragmentation test day in Bristol is scheduled for Monday 23rd March. Drop-off window is 12:30 - 13:00.

Our next DNA Fragmentation test day in Frome is scheduled for Friday 20th March. Drop-off window is 18:30 - 19:00.

Appointments can now be booked online. Your appointment time simply helps us manage the number of samples arriving that day. Please aim to arrive within the drop-off window provided in your instructions rather than exactly at your appointment time.

A £115 deposit secures your place, which will be deducted from the total cost of your test.

All tests are booked using the same sample drop-off appointment. The most appropriate test level can be confirmed after booking.

Once your booking is confirmed, we will send your sample collection kit and instructions.

Samples are produced at home for privacy and brought to the clinic within 45 minutes.

If you have any questions about sample collection or logistics, we’re very happy to talk you through it — just get in touch.

How the test works

1

Book Your Test

Reserve your place online with a £115 deposit. We’ll then arrange delivery of your sample collection kit and confirm the most appropriate test level with you.

2

Collect Your Sample at Home

Produce your sample in the privacy of your own home and bring it to the clinic within 45 minutes of production.

3

Laboratory Analysis & Results

Your sample is analysed by Examen’s specialist laboratory using the Comet assay. Results will be shared with you once available, and interpretation can be arranged if required.

Hidden Sperm Damage: Could It Be DNA Fragmentation?

Unexplained infertility can be frustrating, especially when test results seem normal. Our featured article sheds light on sperm DNA fragmentation — microscopic breaks in sperm DNA that can reduce fertility, increase miscarriage risk, and go unnoticed without advanced testing.

Could It Be Sperm DNA Fragmentation?

Featured Post

Could It Be Sperm DNA Fragmentation?

Sperm DNA fragmentation may underlie unexplained infertility or recurrent miscarriage by impairing embryo and placenta development.

Read more

Not sure if you need this test?

We have a wealth of resources to help you understand whether Sperm DNA Fragmentation could be affecting your ability to conceive.

If you have had any of the following then a sperm DNA fragmentation test should be considered:

  • Recurrent miscarriages or chemical pregnancies.
  • Ectopic pregnancy.
  • Inability to conceive or a diagnosis of 'unexplained infertility'.
  • Embryos that fail to develop 72 hours after fertilisation.
  • Morphology (normal forms) of 4% or below.
  • Varicocele (varicosed veins in or around the scrotum)


For more information please read Examen's patient brochure.

Read Brochure

Our Clinical Outcomes

Improved with personalised advice

75%

After structured fertility guidance

Average reduction observed

−6.5%

Across repeat DNA fragmentation tests

Improved with acupuncture added

80%

When acupuncture was included

Average reduction with acupuncture

−7.4%

In combined treatment group

No improvement observed

25%

Showed little change or an increase

These figures come from anonymised repeat sperm DNA fragmentation tests in men who received structured fertility guidance through our clinics, with some also undergoing acupuncture treatment. Individual outcomes vary.
View Clinical Audit

Price List

The Exact Test

A comprehensive test that detects total sperm dna fragmentation (both single- and double-stranded damage) associated with difficulty conceiving.

£495

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The Extend Test

A specialist test focused solely on double-stranded DNA damage, which has been strongly linked to miscarriage and recurrent pregnancy loss.

£620

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The Extensiv Test

A discounted value bundle that combines both the Exact and Extend tests in one convenient booking.

£920

Book Sample Drop-Off

Get in touch for more help